Gwan Cheol Park – World Conference on Pharmacometrics

2016

Pharmacokinetic Modeling and Simulation Analysis of LCB01-0371, a New Oxazolidinone Antibiotic Under Clinical Development

Posted on August 19, 2016 by Gwan Cheol Park

Aims: LCB01-0371 is a new oxazolidinone antibiotic with cyclic amidrazone under clinical development. It exerts its anti-bacterial activity by binding to bacter...

2016

A simulation study to evaluate treatment effect of tamoxifen by CYP2D6 genotypes compared with AIs

Posted on August 19, 2016 by Gwan Cheol Park

Aims: Tamoxifen is a prodrug, and active metabolites including endoxifen are known to exert its therapeutic effect of tamoxifen. Tamoxifen is converted to endox...